Cell Culture Media, Supplements, and Reagents
American Research Products Inc Mouse FGF21 ELISA Kit
This Mouse Fibroblast Growth Factor 21 (FGF21) ELISA Kit is a precoated Sandwich ELISA assay designed to detect and quantify the target analyte in serum plasma tissue homogenates cell lysates cell culture supernatants and other biological fluids This product is for Research Use Only
Medchemexpress LLC MCB-3681 | 790704-42-6 | MFCD32062731 | 99.2% | 626.60 g·mol⁻¹ | C31H32F2N4O8 | 5 MG
MCB-3681 is the antibacterial active substance of Oxaquin, active against gram-positive bacteria. It is provided as a research-grade small molecule with molecular formula C31H32F2N4O8 and molecular weight 626.60 g·mol⁻¹, supplied at high reported purity for laboratory studies.
- High purity suitable for analytical and biological assays.
- Demonstrated activity against gram-positive bacteria.
- Well-defined molecular formula and molecular weight for reproducibility.
- Available in multiple small pack sizes for preclinical research.
- Stable solid form for convenient storage and handling.
Medchemexpress LLC 5-Pyrimidinecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-... | 2556836-50-9 | 98.6% | 597.11 | 100 MG
DGY-06-116 is an irreversible covalent and selective Src inhibitor with an IC50 of 3 nM. It demonstrates potent antiproliferative effects in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC) cell lines, effectively inhibiting Src kinase activity and signaling.
- Irreversible covalent and selective Src inhibitor
- Potent antiproliferative effects in various cancer cell lines
- Induces potent Src binding and inhibition of Src signaling
- Effective in vivo inhibition of Src with a short half-life
Medchemexpress LLC Carbetocin (acetate) | 1631754-28-3 | 99.6% | 1048.21 | 5 MG
Carbetocin acetate is an oxytocin (OT) analogue and an oxytocin receptor agonist with a Ki of 7.1 nM. It shows high affinity to the chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). This compound has potential for research related to postpartum hemorrhage and can cross the blood-brain barrier, exhibiting antidepressant-like activity through the activation of oxytocin receptors in the central nervous system.
- Oxytocin (OT) analogue and oxytocin receptor agonist.
- Ki of 7.1 nM for oxytocin receptor.
- High affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM).
- Potential for postpartum hemorrhage research.
- Can cross the blood-brain barrier.
- Produces antidepressant-like activity via activation of oxytocin receptors in the CNS.
- Agonist with significantly higher stability and longer duration of action compared to oxytocin.
Medchemexpress LLC Huperzine B | 103548-82-9 | MFCD01716207 | 98.7% | 256.34 g/mol | C16H20N2O | 10 MG
Huperzine B is a Lycopodium alkaloid and a selective acetylcholinesterase (AChE) inhibitor used as a research reagent. It is supplied as a purified white to off-white solid with high purity and is suitable for biochemical and pharmacological studies.
- Selective acetylcholinesterase inhibitor.
- High purity (98.7%).
- White to off-white solid form.
- Available in milligram quantities and in DMSO solution for assays.
- Suitable for biochemical and pharmacological research applications.
Medchemexpress LLC Isomogroside V | 1126032-65-2 | 10 MG
Isomogroside V is a sweetener extracted from the plant *Siraitia grosvenorii (Swingle)*. This product is intended for research use only and is not for sale to patients.
- Extracted from *Siraitia grosvenorii (Swingle)*
- Suitable for research use only
- Appears as a solid
- Color is white to off-white
- Classified as a triterpene
Medchemexpress LLC Penicillin G benzathine | 1538-09-6 | 1 ML
Penicillin G benzathine, also known as Benzathine benzylpenicillin, is an antibiotic used against many bacterial infections.
- For research use only.
- Displays activity and antibacterial effects in CD-I mice infected with Staphylococcus aureus Smith.
Medchemexpress LLC Meropenem-d6 (SM 7338-d6) | 1217976-95-8 | 98.3% | 389.50 | 1 MG
Meropenem-d6 is a deuterium-labeled version of Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic known for its broad-spectrum antibacterial activity. It demonstrates activity against various susceptible and resistant bacteria, including *N. gonorrhoeae*, *H. influenzae*, and *H. ducreyi*, with reported MIC values ranging from 0.015 mg/mL to 0.12 mg/mL.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC CRBN modulator-1 | 2407829-65-4 | 98.0% | 324.29 | 50 MG
CRBN modulator-1 is a thalidomide analog and a cereblon (CRBN) modulator. This compound, identified as compound 10 from WO2020006262A1, is presented as a solid with a light green to green color. It is intended for research use only.
- Thalidomide analog
- CRBN modulator
- IC50 of 3.5 μM
- Ki of 0.98 μM
- Targets Cereblon
- Solid appearance
- Light green to green color
Medchemexpress LLC HPK1-IN-7 | 2320462-65-3 | 99.33% | 458.47 | 100 MG
HPK1-IN-7 is a potent, orally active hematopoietic progenitor kinase 1 inhibitor with excellent family and kinome selectivity. It demonstrates robust efficacy in tumor models in combination with anti-PD1.
- Potent and selective inhibitor
- Orally active
- Shows selectivity against IRAK4 and GLK
- Enhances anti-PD1 efficacy in syngeneic tumor models
Medchemexpress LLC Penicillin G procaine hydrate | 6130-64-9 | 1 ML
Penicillin G Procaine hydrate (PGP hydrate) is a β-lactam antibiotic and a sustained-release formulation. In vivo, Penicillin G procaine (hydrate) hydrolyzes to release penicillin G and procaine, which delays the absorption of penicillin G.
- DMSO solubility: 250 mg/mL (424.65 mM); requires ultrasonic; use newly opened DMSO due to hygroscopic nature affecting solubility
- H2O solubility: 3.14 mg/mL (5.33 mM); requires ultrasonic
- Powder storage: -20°C for 3 years or 4°C for 2 years
- In solvent (stock solution) storage: -80°C for 2 years or -20°C for 1 year
- Aliquot and store prepared solutions to prevent inactivation from repeated freeze-thaw cycles
Medchemexpress LLC MKI-1 (MASTL Kinase Inhibitor-1) | 1190277-80-5 | 98.1% | 302.33 | 100 MG
MKI-1 is a novel small-molecule inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) with an IC50 of 9.9 μM. It demonstrates antitumor and radiosensitizer activities by activating PP2A in breast cancer.
- Inhibits MASTL activity.
- Suppresses various oncogenic properties in cancer cells.
- Reduces both serine 62-phosphorylation and total c-Myc, alongside a decrease in ENSA phosphorylation.
- Decreases c-Myc stability through PP2A activation.
- Reduces tumor growth and enhances radiosensitivity in xenograft models.
- Exhibits low gross toxicity in treated animal models, with no notable changes in body weight.
Medchemexpress LLC MI-389 | 2222635-92-7 | 99.3% | 654.69 | 50 MG
MI-389 is a PROTAC translation termination factor GSPT1 degrader. It disrupts a target that is a shared dependency in various AML and ALL cell lines, and its action depends on the CRL4CRBN E3 ligase. This product is for research use only and is not sold to patients.
- Targets cereblon
- Exhibits antiproliferative activity in Kasumi 1 cells with an EC50 of 21.3 nM
- Appears as a yellow to orange solid
- Has a molecular formula of C35H35FN6O6
- Boasts a purity of 99.34%
- Soluble in DMSO at 66.67 mg/mL (101.83 mM)